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Science Sparks @ ACTREC
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 14th July 2025 |
Vol. No. 14 ; Issue No.691 |
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Publications
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1. Rossi L, Bijman R, Chopra S, Mittal P, Panda S, Westerveld H, Christianen M, Kolkman-Deurloo IK, Breedveld S, Nout R, Heijmen B (2025). Rule-based AI automated adaptive treatment planning for image guided cervical cancer brachytherapy. Brachytherapy.
2. Gundavda K, Rajavelu N, Chopde A, Rane P, Ostwal V, Ramaswamy A, Gudi S, Kaushal RK, Deodhar K, Chaudhari V, Shrikhande S, Bhandare M (2025). Intraoperative revision of a positive proximal resection margin is associated with improved survival in patients undergoing resection for gastroesophageal junction and proximal third gastric adenocarcinoma. Journal of Gastrointestinal Surgery. 29(9): 102123
3. Chaubal R, Talker E, Chitra J, Kadam R, Gardi N, Ursekar R, Kadam A, Singh A, Sale S, Pandey S, Madhav M, Raja A, Mukhare R, Parab P, Shetty N, Gala K, Kulkarni S, Gandhi KA, Gulia S, Joshi S, Shet T, Gupta S (2025). Genomic landscape of hormone therapy-resistant HR-positive, HER2-negative breast cancer. Breast Cancer Research and Treatment.
4. Kar S, Chakraborty A, Lakshminarayanan N, Rajesh C, Chaudhuri P, Ray MK, Bose K, Banerjee S, Basu S, Mallia MB (2025). Convenient one-pot synthesis of 1-(4-(4-(2-[18F]fluoroethoxy)phenyl)piperazin-1-yl)ethanone ([18F]FEt-PPZ) for imaging tumors expressing sigma-1 receptors. RSC Advances. 15(29):23943-23953.
5. Khanna D, Vishwakarma R, Sharma AN, Budukh A, Verma RK, Riguvanshi A, Mahmood F, Chaturvedi P, Pradhan S (2025). Epidemiology of adolescent and young adult cancer and associated disparities in cancer pattern and care in India: findings from Varanasi's population-based cancer registry, 2017-2019. Cancer Causes and Control.
Thesis
Pratham Prakash Phadte. 2025. Investigating role of MAPK-ERK & PIK3CA-AKT signalling on autophagic flux in Ovarian Cancer Stem Cells.( LIFE09201804001) (Guide: Dr. Pritha Ray)
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Interesting Reads
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Dimopoulos MA, Terpos E, Boccadoro M, Moreau P, Mateos MV, Zweegman S, Cook G, Engelhardt M, Delforge M, Hajek R, Schjesvold F, Gay F, Manier S, Weisel KC, Kaiser M, van de Donk NWCJ, Zamagni E, Rodriguez-Otero P, Perrot A, Driessen C, Bila J, Laane E, Dytfeld D, Touzeau C, Beksac M, Raab MS, Cavo M, Mohty M, Spencer A, Ludwig H, Einsele H, San-Miguel J, Sonneveld P (2025). EHA-EMN Evidence-Based Guidelines for diagnosis, treatment and follow-up of patients with multiple myeloma. Nat Rev Clin Oncol.
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Video of the Week
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| ADCs: Current and Future Strategies for Patients with Endocrine-Refractory HR+ mBC |
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Do You Know?
In 1918, Physicist Gioacchino Failla, who worked at Memorial Sloan Kettering, developed the first external-beam radium therapy device, known as a “radium element pack.” The device is used to treat cancers located in the chest, brain, and abdomen.
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Cancer News
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Novel CDK2 inhibitor INCB123667 shows promise in ovarian cancer.
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Targeted Oncology, 11/07/2025
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The investigational CDK2 inhibitor INCB123667 showed encouraging anti-tumor activity with manageable toxicity in patients with heavily pretreated resistant/refractory ovarian cancer, according to results from a phase 1a/b dose escalation/expansion study...
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Gene Model Predicts Risk in Head and Neck Cancer
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docwirenews, 09/07/2025
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Within the training set, the research team identified 10,185 differentially expressed genes and 993 key module genes in HNSCC. They overlapped these genes with 603 known PMRGs to identify a total of 42 candidate genes and used regression analyses to narrow these to four feature...
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2025 Advanced Centre for Treatment, Research and Education in Cancer (ACTREC)
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